Dichloromethane → 4(5-Chloro-2,3-methylenedioxypyrid-4-ylamino)-6-methoxy-7-(piperidin-4-ylmethoxy)quinazoline
Reaction equation
[C:8]([O:9][C:10](=[O:11])[N:15]1[CH2:16][CH2:17][CH:18]([CH2:21][O:22][c:23]2[c:24]([O:44][CH3:45])[cH:25][c:26]3[c:27]([NH:33][c:34]4[c:35]5[c:36]([n:37][cH:38][c:39]4[Cl:40])[O:41][CH2:42][O:43]5)[n:28][cH:29][n:30][c:31]3[cH:32]2)[CH2:19][CH2:20]1)([CH3:12])([CH3:13])[CH3:14].[CH2:46]([Cl:47])[Cl:48].[OH:1][C:2]([C:3]([F:4])([F:5])[F:6])=[O:7]>>[NH:15]1[CH2:16][CH2:17][CH:18]([CH2:21][O:22][c:23]2[c:24]([O:44][CH3:45])[cH:25][c:26]3[c:27]([NH:33][c:34]4[c:35]5[c:36]([n:37][cH:38][c:39]4[Cl:40])[O:41][CH2:42][O:43]5)[n:28][cH:29][n:30][c:31]3[cH:32]2)[CH2:19][CH2:20]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-e578701eff1849ff9a2a397289b24270
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)