Formaldehyde → 4-bis(phenylmethyl)amino-1-ethoxymethyl-1H-imidazo[4,5-c]quinolin-2-methanol

HRID 169815

Reaction equation

HRID 169815 reaction equation
[CH2:38]=[O:39].[Li:1][CH2:2][CH2:3][CH2:4][CH3:5].[O:40]1[CH2:41][CH2:42][CH2:43][CH2:44]1.[c:6]1([CH2:12][N:13]([c:14]2[n:15][c:16]3[cH:17][cH:18][cH:19][cH:20][c:21]3[c:22]3[c:23]2[n:24][cH:25][n:26]3[CH2:27][O:28][CH2:29][CH3:30])[CH2:31][c:32]2[cH:33][cH:34][cH:35][cH:36][cH:37]2)[cH:7][cH:8][cH:9][cH:10][cH:11]1>>[c:6]1([CH2:12][N:13]([c:14]2[n:15][c:16]3[cH:17][cH:18][cH:19][cH:20][c:21]3[c:22]3[c:23]2[n:24][c:25]([CH2:38][OH:39])[n:26]3[CH2:27][O:28][CH2:29][CH3:30])[CH2:31][c:32]2[cH:33][cH:34][cH:35][cH:36][cH:37]2)[cH:7][cH:8][cH:9][cH:10][cH:11]1

Participants

5

Reactant 4

HCID 712FormaldehydeHCID 8028TetrahydrofuranHCID 18995666N,N-bis(phenylmethyl)-1-ethoxymethyl-1H-imidazo[4,5-c]quinolin-4-amineHCID 178418339Butyllithium

Product 1

HCID 189956654-bis(phenylmethyl)amino-1-ethoxymethyl-1H-imidazo[4,5-c]quinolin-2-methanol

Sources & evidence

ORD record
ord-10cc5b0986cb49c5830aa708a4a939eb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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