Hydrazine hydrate (1:1) → HCID 178424178, compound
Reaction equation
O[C:2](=[C:4]1[C:9](=[O:10])[CH2:8][CH:7]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=2[CH3:17])[CH2:6][C:5]1=O)[CH3:3].O.[NH2:20][NH2:21]>C(O)C>[CH3:3][C:2]1[C:4]2[C:9](=[O:10])[CH2:8][CH:7]([C:11]3[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=3[CH3:17])[CH2:6][C:5]=2[NH:21][N:20]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
A solution of 2-(1-hydroxyethylidene)-5-(2-methylphenyl)cyclohexane-1,3-dione (0.45 g) and hydrazine hydrate (0.1 g) in ethanol (10 ml) was refluxed for 15 minutes. Under reduced pressure, the solvent was evaporated, and the residue was recrystallized from ethyl acetate-hexane to give colorless crystals of 3-methyl-6-(2-methylphenyl)-4,5,6,7-tetrahydroindazol-4-one (0.40 g).