2-Butanamine, 2-methyl- → N-(2,6-Diisopropyl-phenyl)-N'-tert.-pentyl-thiourea

HRID 1701560

Reaction equation

HRID 1701560 reaction equation
[CH:1]([C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([CH:10]([CH3:12])[CH3:11])[C:5]=1[N:13]=[C:14]=[S:15])([CH3:3])[CH3:2].[C:16]([NH2:21])([CH2:19][CH3:20])([CH3:18])[CH3:17]>C(N(CC)CC)C>[CH:1]([C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([CH:10]([CH3:11])[CH3:12])[C:5]=1[NH:13][C:14]([NH:21][C:16]([CH2:19][CH3:20])([CH3:18])[CH3:17])=[S:15])([CH3:2])[CH3:3]

Participants

4

Reactant 2

HCID 689862-Butanamine, 2-methyl-HCID 1411942-Isothiocyanato-1,3-bis(propan-2-yl)benzene

Product 1

HCID 20347005N-(2,6-Diisopropyl-phenyl)-N'-tert.-pentyl-thiourea

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Conditions

Temperature
-10 °C

Procedure

11.0 g of 2,6-diisopropyl-phenyl isothiocyanate and 10 g of tert.-pentylamine are warmed with 5 ml of triethylamine for 10 minutes at 100°. After standing for 12 hours, the mixture which has partially crystallised out is stirred with petroleum ether and cooled to -10° C., and the product is filtered off and dried.

Workup

  1. customthe mixture which has partially crystallised out
  2. filtrationthe product is filtered off
  3. customdried

Sources & evidence

ORD record
ord-d9b862f4e5314eeca858816b39825fce
Source dataset
uspto-grants-1980_03
Patent number
US04194008

Linked notes

Loading…