Methylamine → HCID 178482527, compound

Reaction equation

CO[C:3]1[C:7](OC)=[N:6][S:5](=[O:11])(=[O:10])[N:4]=1.[CH3:12][C:13]1[C:14]([CH2:18][S:19][CH2:20][CH2:21][NH2:22])=[N:15][O:16][N:17]=1.[CH3:23][NH2:24]>>[CH3:12][C:13]1[C:14]([CH2:18][S:19][CH2:20][CH2:21][NH:22][C:3]2[C:7]([NH:24][CH3:23])=[N:6][S:5](=[O:11])(=[O:10])[N:4]=2)=[N:15][O:16][N:17]=1

Participants

Reactant 3

HCID 6329Methylamine

HCID 122305383,4-Dimethoxy-1,2,5-thiadiazole 1,1-dioxide

HCID 131028982-[(4-Methyl-1,2,5-oxadiazol-3-yl)methylthio]ethylamine

Product 1

HCID 178482527HCID 178482527, compound

Procedure

When a methanolic suspension of 3,4-dimethoxy-1,2,5-thiadiazole 1,1-dioxide is successively treated with an equimolar amount of 2-[(4-methyl-1,2,5-oxadiazol-3-yl)methylthio]ethylamine [prepared in Step B] and excess methylamine by the general procedure of Example 2, the title compound is thereby produced.

Sources & evidence

ORD record: ord-245c1dcd02234bd7b810dcdbac0c98c8
Source dataset: uspto-grants-1983_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04380639

Reaction notes

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