Methane → HCID 178457613, compound

HRID 1702839

Reaction equation

HRID 1702839 reaction equation
[Cl:1][C:2]1[C:11]([CH3:12])=[N:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:3]=1.C.[CH2:14]([NH:17][C:18]([NH2:20])=[S:19])[CH:15]=[CH2:16]>CC(C)=O>[ClH:1].[CH3:12][C:11]1[C:2]([S:19][C:18](=[NH:20])[NH:17][CH2:14][CH:15]=[CH2:16])=[N:3][C:4]2[C:9]([N:10]=1)=[CH:8][CH:7]=[CH:6][CH:5]=2

Participants

5

Reactant 3

HCID 297MethaneHCID 2362762-Chloro-3-methylquinoxalineHCID 1549517Allylthiourea

Product 1

HCID 178457613HCID 178457613, compoundYield 75.6%

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent2×

Procedure

2-Chloro-3-methylquinoxaline (5.359 g., 0.03 mole) was dissolved in 75 ml. of acetone, treated with Norit and filtered. The filtrate was added to a solution of 3.485 g. (0.03 mole) of allylthiourea in 50 ml. of acetone while the solution was stirred at room temperature under N2. A precipitate had formed at the end of 2 hours. Stirring was continued for 31/2 hours. The solid that was filtered off was washed with acetone, then ether and dried, to give 6.68 g. (75.6% yield) of product as a pink solid, m.p. 113°-114° C.

Workup

  1. filtrationfiltered
  2. additionThe filtrate was added to a solution of 3.485 g
  3. customA precipitate had formed at the end of 2 hours
  4. custom2 hours
  5. filtrationThe solid that was filtered off
  6. washwas washed with acetone
  7. dry with materialether and dried
  8. customto give 6.68 g

Sources & evidence

ORD record
ord-462a5cbd10ab49dbacc8f96e6d642807
Source dataset
uspto-grants-1982_09
Patent number
US04349674

Linked notes

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