4-(Trifluoromethyl)phenol → HCID 86736168, compound
Reaction equation
Br[CH:2]([C:7]1[CH:12]=[CH:11][C:10]([O:13][CH2:14][CH:15]([O:17][C:18]2[CH:23]=[CH:22][C:21]([C:24]([F:27])([F:26])[F:25])=[CH:20][CH:19]=2)[CH3:16])=[CH:9][CH:8]=1)[C:3]([O:5][CH3:6])=[O:4].[F:28][C:29]([F:38])([F:37])[C:30]1[CH:31]=[CH:32][C:33]([OH:36])=[CH:34][CH:35]=1>O1CCCC1>[F:28][C:29]([F:37])([F:38])[C:30]1[CH:35]=[CH:34][C:33]([O:36][CH:2]([C:7]2[CH:12]=[CH:11][C:10]([O:13][CH2:14][CH:15]([O:17][C:18]3[CH:23]=[CH:22][C:21]([C:24]([F:27])([F:26])[F:25])=[CH:20][CH:19]=3)[CH3:16])=[CH:9][CH:8]=2)[C:3]([O:5][CH3:6])=[O:4])=[CH:32][CH:31]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
As described in Example 71, methyl bromo{p-[2-(α,α,α-trifluoro-p-tolyloxy)propoxy]phenyl}acetate (0.017 mole) is reacted with 2.75 g of α,α,α-trifluoro-p-cresol in 75 ml of tetrahydrofuran at 80° C. for 24 hrs to give the product as a viscous oil.