Methylamine → HCID 57178653, compound
Reaction equation
O=[C:2]1[C:7]2[N:8]=[CH:9][S:10][C:6]=2[CH2:5][CH2:4][CH2:3]1.[CH3:11][NH2:12]>C(O)C>[CH3:11][N:12]=[C:2]1[C:7]2[N:8]=[CH:9][S:10][C:6]=2[CH2:5][CH2:4][CH2:3]1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
6 g (0.039 mole) of the ketone obtained in step (d) are dissolved in 50 ml anhydrous ethanol and treated for 30 minutes with a gaseous methylamine stream. After evaporation to dryness, the residue is taken up into ether and filtered, to give 5.6 g (86%) of product, M.p. 233°-235° C.
Workup
- customAfter evaporation to dryness
- filtrationfiltered
Sources & evidence
- ORD record
- ord-b61f206962e54c0791738650f81f1812
- Source dataset
- uspto-grants-1980_06
- Patent number
- US04208420
Reaction notes
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