Oxalyl chloride → HCID 20096059, compound
Reaction equation
C(Cl)(=O)[C:2](Cl)=[O:3].[Cl:7][C:8]1[C:16]([N+:17]([O-:19])=[O:18])=[CH:15][CH:14]=[C:13]([Cl:20])[C:9]=1[C:10]([NH2:12])=[O:11]>C(Cl)Cl>[Cl:7][C:8]1[C:16]([N+:17]([O-:19])=[O:18])=[CH:15][CH:14]=[C:13]([Cl:20])[C:9]=1[C:10]([N:12]=[C:2]=[O:3])=[O:11]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
3.5 ml of oxalyl chloride are added dropwise at room temperature over a period of 30 minutes to a suspension of 7.68 g of 2,6-dichloro-3-nitrobenzoic acid amide in 570 ml of methylene chloride. The batch is then heated at reflux temperature for 18 hours and the solvent is subsequently distilled off in vacuo, affording 8.6 g of crude 2,6-dichloro-3-nitrobenzoyl isocyanate which can be used directly in the subsequent reactions.