Phenylboronic Acid → HCID 46314744, compound

Reaction equation

Br[C:2]1[CH:9]=[CH:8][C:5]([C:6]#[N:7])=[C:4]([CH3:10])[CH:3]=1.[C:11]1(B(O)O)[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>>[CH3:10][C:4]1[CH:3]=[C:2]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH:9]=[CH:8][C:5]=1[C:6]#[N:7]

Participants

Reactant 2

HCID 66827Phenylboronic Acid

HCID 1442674-Bromo-2-methylbenzonitrile

Product 1

HCID 46314744HCID 46314744, compound

Procedure

The title compound was prepared in a similar manner to that described in Reference Example 2 using 4-bromo-2-methylbenzonitrile instead of tert-butyl N-(4-bromobenzyl) carbamate and phenylboronic acid instead of 3-benzyloxyphenylboronic acid.

Sources & evidence

ORD record: ord-aef0bfc3e05c4242bde52f12c334cda9
Source dataset: uspto-grants-2010_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07795236B2

Reaction notes

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