Dichloromethane → N-[2-amino-5-(trifluoromethyl)benzyl]-N-[3,5-bis(trifluoromethyl)benzyl]-acetamide

HRID 171518

Reaction equation

[CH2:43]([Cl:44])[Cl:45].[CH3:29][C:30](=[O:31])[O:32][C:33](=[O:34])[CH3:35].[CH3:36][CH2:37][N:38]([CH2:39][CH3:40])[CH2:41][CH3:42].[NH2:1][c:2]1[c:3]([CH2:4][NH:5][CH2:6][c:7]2[cH:8][c:9]([C:17]([F:18])([F:19])[F:20])[cH:10][c:11]([C:13]([F:14])([F:15])[F:16])[cH:12]2)[cH:21][c:22]([C:25]([F:26])([F:27])[F:28])[cH:23][cH:24]1>>[NH2:1][c:2]1[c:3]([CH2:4][N:5]([CH2:6][c:7]2[cH:8][c:9]([C:17]([F:18])([F:19])[F:20])[cH:10][c:11]([C:13]([F:14])([F:15])[F:16])[cH:12]2)[C:30]([CH3:29])=[O:31])[cH:21][c:22]([C:25]([F:26])([F:27])[F:28])[cH:23][cH:24]1

Participants

Reactant 4

HCID 6344Dichloromethane

HCID 7918Acetic Anhydride

HCID 8471Triethylamine

HCID 59343853[2-Amino-5-(trifluoromethyl)benzyl][3,5-bis(trifluoromethyl)benzyl]amine

Product 1

HCID 86615399N-[2-amino-5-(trifluoromethyl)benzyl]-N-[3,5-bis(trifluoromethyl)benzyl]-acetamide

Sources & evidence

ORD record: ord-17bee28ba4084879bcb51602f6157ccb
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (9/10)
DOI: 10.1039/C8SC04228D

Linked notes

Loading…