Sodium Sulfite → HCID 86749374, compound
Reaction equation
[F:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6]Br)=[C:4]([N+:10]([O-:12])=[O:11])[CH:3]=1.[S:13]([O-:16])([O-:15])=[O:14].[Na+:17].[Na+]>O>[F:1][C:2]1[CH:9]=[CH:8][C:5]([CH2:6][S:13]([O-:16])(=[O:15])=[O:14])=[C:4]([N+:10]([O-:12])=[O:11])[CH:3]=1.[Na+:17]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
A solution of 4-fluoro-2-nitrobenzylbromide (50.1 g) and sodium sulfite (27.3 g) in water (200 ml) was heated under reflux for 2.5 hours and cooled to room temperature. The solvent was removed under reduced pressure and ethanol (100 ml) was added to the crude product.
Workup
- temperatureunder reflux for 2.5 hours
- customThe solvent was removed under reduced pressure and ethanol (100 ml)
- additionwas added to the crude product
Sources & evidence
- ORD record
- ord-d2b5e084fb4946508147eb1d65cfcb51
- Source dataset
- uspto-grants-1996_04
- Patent number
- US05504095
Reaction notes
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