1,3-Diisopropylbenzene → 1,3-Diisopropylbenzene

HRID 1725154

Reaction equation

HRID 1725154 reaction equation
[O-:1][OH:2].[CH:3]([C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([CH:12]([CH3:14])[CH3:13])[CH:7]=1)([CH3:5])[CH3:4].[CH:15]([C:18]1[CH:23]=[CH:22][CH:21]=[C:20]([CH:24]([CH3:26])[CH3:25])[CH:19]=1)([CH3:17])[CH3:16].CC1C2COC(=O)C=2C(O[C@@H]2O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]2O)=C(C/C=C(/CCC(O)=O)\C)C=1OC>>[O-:1][OH:2].[O-:1][OH:2].[CH:12]([C:8]1[CH:9]=[CH:10][CH:11]=[C:6]([CH:3]([CH3:5])[CH3:4])[CH:7]=1)([CH3:14])[CH3:13].[O-:1][OH:2].[CH:24]([C:20]1[CH:21]=[CH:22][CH:23]=[C:18]([CH:15]([CH3:17])[CH3:16])[CH:19]=1)([CH3:26])[CH3:25].[CH:12]([C:8]1[CH:9]=[CH:10][CH:11]=[C:6]([CH:3]([CH3:5])[CH3:4])[CH:7]=1)([CH3:14])[CH3:13]

Participants

6

Reactant 3

HCID 74501,3-DiisopropylbenzeneHCID 6442661Mycophenolic acid glucuronideHCID 71436539m-Diisopropylbenzene monohydroperoxide

Product 3

HCID 74501,3-DiisopropylbenzeneHCID 53471113Hydroperoxide,1,1'-[1,3-phenylenebis(1-methylethylidene)]bis-HCID 71436539m-Diisopropylbenzene monohydroperoxide

Procedure

The raw material liquid for oxidation usually contains 20 to 60% by weight of m-diisopropylbenzene monohydroperoxide and 10 to 40% by weight of m-diisopropylbenzene. As usual reaction conditions, a temperature of 70 to 110° C., a pressure of 0 to 1 MPaG, a residence time of about 0.01 to 50 hours and the like are illustrated. As an apparatus used in the oxidation step, for example, a flowing type or batch type reaction vessel or reaction column can be listed. The oxidation reaction mixture obtained in the oxidation step usually contains 3 to 30% by weight of m-diisopropylbenzene dihydroperoxide and 20 to 60% by weight of m-diisopropylbenzene monohydroperoxide and 35% by weight or less of m-diisopropylbenzene.

Workup

  1. customAs usual reaction conditions
  2. customa temperature of 70 to 110° C.
  3. customa residence time of about 0.01 to 50 hours
  4. customa flowing type or batch type reaction vessel or reaction column
  5. customThe oxidation reaction mixture

Sources & evidence

ORD record
ord-84d300448354445b89e57a2f3dfe2257
Source dataset
uspto-grants-2009_02
Patent number
US07488853B2

Linked notes

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