HCID 67842554, compound → HCID 19016526, compound
Reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([NH:10]N=C(OCC)C(=O)CCC)=[CH:6][CH:5]=1)([O-:3])=[O:2]>Cl>[CH2:5]([C:4]1[C:6]2[C:7](=[CH:8][CH:9]=[C:4]([N+:1]([O-:3])=[O:2])[CH:5]=2)[NH:10][CH:9]=1)[CH3:6]Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
The 4-nitrophenylhydrazone of ethyl 2-oxopentanoate (D29) (0.72 g, 2.60 mM) was heated to reflux for 16 h in concentrated hydrochloric acid. After cooling to room temperature the precipitated solid was filtered off. Chromatography on silica using dichloromethane as eluant gave the title compound as a yellow solid (0.22 g; 45%).
Workup
- filtrationwas filtered off
Sources & evidence
- ORD record
- ord-15b103780a3c45b68d45661a388de054
- Source dataset
- uspto-grants-1994_07
- Patent number
- US05328922
Reaction notes
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