Dibutylamine → 1-Di-n-butylamino-5,5,7,7-tetramethyl-2-octene

HRID 1729343

Reaction equation

HRID 1729343 reaction equation
Cl[CH2:2][CH:3]=[CH:4][CH2:5][C:6]([CH3:13])([CH3:12])[CH2:7][C:8]([CH3:11])([CH3:10])[CH3:9].[CH2:14]([NH:18][CH2:19][CH2:20][CH2:21][CH3:22])[CH2:15][CH2:16][CH3:17].[O-2].[Mg+2]>C1COCC1.CCCCCC>[CH2:14]([N:18]([CH2:19][CH2:20][CH2:21][CH3:22])[CH2:2][CH:3]=[CH:4][CH2:5][C:6]([CH3:13])([CH3:12])[CH2:7][C:8]([CH3:11])([CH3:10])[CH3:9])[CH2:15][CH2:16][CH3:17]

Participants

6

Reactant 3

HCID 8148DibutylamineHCID 1359701-Chloro-5,5,7,7-tetramethyl-2-octeneHCID 6850729Magnesium monoxide

Product 1

HCID 538384691-Di-n-butylamino-5,5,7,7-tetramethyl-2-octene

Reagents, catalysts & solvents 2

HCID 8028TetrahydrofuranSolventHCID 8058HexaneSolvent

Procedure

10 g (49.5 mmol) of 1-chloro-5,5,7,7-tetramethyl-2-octene, 64 g (495 mmol) of di-n-butylamine and 10 g (248 mmol) of magnesium oxide in 30 ml of THF are refluxed for 4.5 h. The mixture is taken up in 200 ml of hexane, extracted twice with 5% strength methanolic NaOH and once with water and dried at 30° C./1 mbar. Yield: quantitative.

Workup

  1. extractionextracted twice with 5% strength methanolic NaOH and once with water
  2. customdried at 30° C./1 mbar

Sources & evidence

ORD record
ord-e55dcf5d82b348bb824bbf01d596c418
Source dataset
uspto-grants-1994_07
Patent number
US05332791

Linked notes

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