2,6-Difluorobenzoyl isocyanate → Teflubenzuron

HRID 1731555

Reaction equation

HRID 1731555 reaction equation
[F:1][C:2]1[CH:12]=[CH:11][CH:10]=[C:9]([F:13])[C:3]=1[C:4]([N:6]=[C:7]=[O:8])=[O:5].[F:14][C:15]1[C:21]([Cl:22])=[C:20]([F:23])[C:19]([Cl:24])=[CH:18][C:16]=1[NH2:17]>C1(C)C=CC=CC=1>[F:14][C:15]1[C:21]([Cl:22])=[C:20]([F:23])[C:19]([Cl:24])=[CH:18][C:16]=1[NH:17][C:7]([NH:6][C:4](=[O:5])[C:3]1[C:2]([F:1])=[CH:12][CH:11]=[CH:10][C:9]=1[F:13])=[O:8]

Participants

4

Reactant 2

HCID 27333692,6-Difluorobenzoyl isocyanateHCID 27740003,5-Dichloro-2,4-difluorobenzenamine

Product 1

HCID 91734Teflubenzuron

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

Three grams (0.016 mol) of 2,6-difluoro-benzoyl isocyanate were added to a solution of 2.95 gm (0.015 mol) of 2,4-difluoro-3,5-dichloroaniline in 50 ml of toluene. The solution thus obtained was stirred for 15 hours at room temperature. Thereafter, the product which precipitated during that time was removed by suction filtration and dried.

Workup

  1. customThe solution thus obtained
  2. customThereafter, the product which precipitated during that time
  3. customwas removed by suction filtration
  4. customdried

Sources & evidence

ORD record
ord-b9ea293f969d45ae913b55afbe5acfe7
Source dataset
uspto-grants-1986_11
Patent number
US04622340

Linked notes

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