Diethylamine → HCID 70597467, compound

Reaction equation

Cl[CH2:2][CH2:3][C:4]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)([OH:6])[CH3:5].[CH2:19]([NH:21][CH2:22][CH3:23])[CH3:20]>>[CH2:19]([N:21]([CH2:22][CH3:23])[CH2:2][CH2:3][C:4]([C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)([OH:6])[CH3:5])[CH3:20]

Participants

Reactant 2

HCID 8021Diethylamine

HCID 70595719HCID 70595719, compound

Product 1

HCID 70597467HCID 70597467, compound

Procedure

2.6 g of 1-chloro-3-p-biphenylyl-butan-3-ol are heated with 30 ml of diethylamine at 150° for 15 hours in an autoclave, and the mixture is cooled and worked up in the customary manner to give 1-diethylamino-3-p-biphenylyl-butan-3-ol.

Workup

temperaturethe mixture is cooled

Sources & evidence

ORD record: ord-70051b2d5b08445194c272e1e123ff35
Source dataset: uspto-grants-1980_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04239759

Reaction notes

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