Chlorotrimethylsilane → HCID 19705234, compound
Reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([C:8](O)([CH3:10])[CH3:9])[CH:5]=[CH:6][CH:7]=1.[Br-:12].[Li+].C[Si](Cl)(C)C>C(#N)C>[Br:12][C:8]([C:4]1[CH:5]=[CH:6][CH:7]=[C:2]([Cl:1])[CH:3]=1)([CH3:10])[CH3:9]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
This compound is prepared in a manner analogous to that of Step A of Example 5, using 8.5 grams (0.05 mole) of 2-(3-chlorophenyl)propan-2-ol, 8.7 grams (0.1 mole) of lithium bromide, and 13.5 grams (0.125 mole) of trimethylsilyl chloride in 100 mL of acetonitrile, yielding 2-bromo-2-(3-chlorophenyl)propane.
Workup
- customThis compound is prepared in a manner analogous to that of Step A of Example 5
Sources & evidence
- ORD record
- ord-51a116ca6e50457e80d725a723cc4358
- Source dataset
- uspto-grants-1996_07
- Patent number
- US05536725
Reaction notes
Loading…