Trifluoroacetic acid → 4'-[(Benzimidazol-1-yl)-methyl]biphenyl-2-carboxylic acid
Reaction equation
[N:1]1([CH2:10][C:11]2[CH:16]=[CH:15][C:14]([C:17]3[C:18]([C:23]([O:25]C(C)(C)C)=[O:24])=[CH:19][CH:20]=[CH:21][CH:22]=3)=[CH:13][CH:12]=2)[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[CH:2]1.FC(F)(F)C(O)=O>>[N:1]1([CH2:10][C:11]2[CH:12]=[CH:13][C:14]([C:17]3[C:18]([C:23]([OH:25])=[O:24])=[CH:19][CH:20]=[CH:21][CH:22]=3)=[CH:15][CH:16]=2)[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[CH:2]1Participants
3
Procedure
Prepared in analogous manner to Example 9 from tert.butyl 4'-[(benzimidazol-1-yl)-methyl]biphenyl-2-carboxylate and trifluoroacetic acid.
Sources & evidence
- ORD record
- ord-3362ab50090e4e659ef56f46273d19f6
- Source dataset
- uspto-grants-1996_07
- Patent number
- US05541229
Reaction notes
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