Dimethyl Sulfoxide → tert-Butyl 4-(4-carbamoylphenoxy)piperidine-1-carboxylate

HRID 173724

Reaction equation

HRID 173724 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([O:14][c:15]2[cH:16][cH:17][c:18]([C:21]#[N:22])[cH:19][cH:20]2)[CH2:12][CH2:13]1.[C:23]([O-:24])(=[O:25])[O-:26].[CH3:31][S:32]([CH3:33])=[O:34].[K+:27].[K+:28].[OH:29][OH:30]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([O:14][c:15]2[cH:16][cH:17][c:18]([C:21]([NH2:22])=[O:24])[cH:19][cH:20]2)[CH2:12][CH2:13]1

Participants

6

Reactant 5

HCID 679Dimethyl SulfoxideHCID 784Hydrogen PeroxideHCID 813Potassium Cation2×HCID 19660Carbonate IonHCID 23019443tert-Butyl 4-(4-cyanophenoxy)piperidine-1-carboxylate

Product 1

HCID 23068080tert-Butyl 4-(4-carbamoylphenoxy)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-1f45259d583a45338f99f611b9e15eba
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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