(+/-)-trans-1,2,3,4,4a,5,6,7,8,8a-Decahydro-2-ethyI-4a-(3-methoxyphenyl)-6-phenyl-6-isoquinolinol → (+/-)-trans-2-Ethyl-4a-(3-methoxyphenyl)-6-phenyl-1,2,3,4,4a,5,8,8a-octahydroisoquinoline
Reaction equation
[CH2:1]([N:3]1[CH2:12][CH2:11][C@@:10]2([C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([O:19][CH3:20])[CH:14]=3)[C@@H:5]([CH2:6][CH2:7][C:8]([C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)(O)[CH2:9]2)[CH2:4]1)[CH3:2]>Cl>[CH2:1]([N:3]1[CH2:12][CH2:11][C@@:10]2([C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([O:19][CH3:20])[CH:14]=3)[C@@H:5]([CH2:6][CH:7]=[C:8]([C:22]3[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=3)[CH2:9]2)[CH2:4]1)[CH3:2]Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
The reaction was conducted as described in Example 2, using 0.79 g (2.16 mmol) of (±)-trans-1,2,3,4,4a,5,6,7,8,8a-decahydro-2-ethyl-4a-(3-methoxyphenyl)-6-phenyl-6-isoquinolinol and 30 ml of 37% HCl, yielding 0.77 g of the title compound. C24H29NO