1-Bromo-3-chloropropane → HCID 85711135, compound

HRID 1740341

Reaction equation

HRID 1740341 reaction equation
[CH3:1][N:2]([CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH3:9])[CH3:3].[Br:10][CH2:11][CH2:12][CH2:13][Cl:14]>CO>[Br-:10].[Cl:14][CH2:13][CH2:12][CH2:11][N+:2]([CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH3:9])([CH3:3])[CH3:1]

Participants

4

Reactant 2

HCID 80061-Bromo-3-chloropropaneHCID 78090N,N-Dimethylhexylamine

Product 1

HCID 85711135HCID 85711135, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Conditions

Temperature
65 °C

Procedure

A 500 mL, 3-necked, round-bottomed flask equipped with air condensers and a magnetic stirring plate was charged with N,N-dimethylhexylamine (199.46 grams, 1.54 moles), 1-bromo-3-chloropropane (243.00 grams, 1.54 moles) and 250 mL of methanol. The reaction was maintained at 65° C. for 24 hours. Solvent was removed by rotary evaporation under reduced pressure to yield a brown, viscous oil. Yield 445.8 grams (1.55 moles, 100%).

Workup

  1. customA 500 mL, 3-necked, round-bottomed flask equipped with air condensers
  2. customSolvent was removed by rotary evaporation under reduced pressure
  3. customto yield a brown, viscous oil

Sources & evidence

ORD record
ord-041ae228686d4fae866668dc87ba5254
Source dataset
uspto-grants-1999_10
Patent number
US05969090

Linked notes

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