O-methylisourea methyl sulfate → Creatine

HRID 1740540

Reaction equation

[NH:1]([CH2:3][C:4]([O-:6])=[O:5])[CH3:2].[Na+].COS(O)(=O)=O.CO[C:16](=[NH:18])[NH2:17]>>[O:5]=[C:4]([CH2:3][N:1]([C:16](=[NH:17])[NH2:18])[CH3:2])[OH:6]

Participants

Reactant 2

HCID 15405421O-methylisourea methyl sulfate

HCID 23667259Sodium Sarcosinate

Product 1

HCID 586Creatine

Procedure

JP 077364 describes the reaction of a solution of sodium sarcosinate with O-methylisourea methyl sulfate at pH 11 to give creatine.

Sources & evidence

ORD record: ord-088d030dcc0f4c12bafb8ee64fc68faa
Source dataset: uspto-grants-1999_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05969182

Linked notes

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