4-Bromobenzohydrazide → 2-(4-Bromophenyl)-5-methyl-1,3,4-oxadiazole

HRID 1741088

Reaction equation

[Br:1][C:2]1[CH:11]=[CH:10][C:5]([C:6]([NH:8][NH2:9])=[O:7])=[CH:4][CH:3]=1.[C:12](OCC)(OCC)(OCC)[CH3:13]>>[Br:1][C:2]1[CH:11]=[CH:10][C:5]([C:6]2[O:7][C:12]([CH3:13])=[N:9][N:8]=2)=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 222194-Bromobenzohydrazide

HCID 66221Triethyl orthoacetate

Product 1

HCID 5406932-(4-Bromophenyl)-5-methyl-1,3,4-oxadiazole

Procedure

The title compound was prepared from 4-bromobenzoic hydrazide and triethyl orthoacetate following a similar procedure to that of Description 35, to afford fine white crystals (77%).

Sources & evidence

ORD record: ord-d85268fe82664a3e985e75737921e420
Source dataset: uspto-grants-1999_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05972951

Linked notes

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