3-Cyanopyridine → (2-Amino-4,5-difluorophenyl)(pyridin-3-yl)methanone

HRID 174266

Reaction equation

HRID 174266 reaction equation
[C:10](#[N:11])[c:12]1[cH:13][n:14][cH:15][cH:16][cH:17]1.[Cl:21][CH:22]=[C:23]([Cl:24])[Cl:25].[Cl:27][CH2:28][Cl:29].[ClH:18].[F:1][c:2]1[c:3]([F:9])[cH:4][c:5]([NH2:8])[cH:6][cH:7]1.[Na+:20].[OH-:19].[OH2:26]>>[F:1][c:2]1[c:3]([F:9])[cH:4][c:5]([NH2:8])[c:6]([C:10]([c:12]2[cH:13][n:14][cH:15][cH:16][cH:17]2)=[O:19])[cH:7]1

Participants

9

Reactant 8

HCID 793-CyanopyridineHCID 313Hydrochloric AcidHCID 923Sodium ionHCID 961HydroxideHCID 962WaterHCID 6344DichloromethaneHCID 6575TrichloroethyleneHCID 774693,4-Difluoroaniline

Product 1

HCID 59788583(2-Amino-4,5-difluorophenyl)(pyridin-3-yl)methanone

Sources & evidence

ORD record
ord-f6260667ca314c56ac4de5776cebe28a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Linked notes

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