4-Aminotetrahydropyran → HCID 71250806, compound
Reaction equation
[C:1]([N:5]1[C:9]([C:10]2[CH:15]=[CH:14][C:13]([O:16][CH3:17])=[CH:12][CH:11]=2)=[C:8]([C:18]2[S:19][CH:20]=[C:21]([CH2:23][CH2:24][C:25]([OH:27])=O)[N:22]=2)[CH:7]=[N:6]1)([CH3:4])([CH3:3])[CH3:2].[NH2:28][CH:29]1[CH2:34][CH2:33][O:32][CH2:31][CH2:30]1>>[C:1]([N:5]1[C:9]([C:10]2[CH:15]=[CH:14][C:13]([O:16][CH3:17])=[CH:12][CH:11]=2)=[C:8]([C:18]2[S:19][CH:20]=[C:21]([CH2:23][CH2:24][C:25]([NH:28][CH:29]3[CH2:34][CH2:33][O:32][CH2:31][CH2:30]3)=[O:27])[N:22]=2)[CH:7]=[N:6]1)([CH3:2])([CH3:3])[CH3:4]Participants
3
Procedure
Using the compound obtained in step 1 and 4-aminotetrahydropyran and by reaction and purification in the same manner as in the method described in Example 1, step 7, the title compound was obtained.
Workup
- customby reaction and purification in the same manner as in the method
Sources & evidence
- ORD record
- ord-d45fd7e12940420aafae633e1e4b745e
- Source dataset
- uspto-grants-2015_10