Tetrahydrofuran → 6-Amino-2,3-dihydro-3,3-dimethyl-1H-isoindol-1-one

HRID 175410

Reaction equation

HRID 175410 reaction equation
[C:13](#[N:14])[c:15]1[cH:16][cH:17][cH:18][cH:19][c:20]1[C:21]([OH:22])=[O:23].[CH3:1][C:2]1([CH3:12])[NH:3][C:4](=[O:11])[c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]21.[Li:24][CH3:25].[O:26]1[CH2:27][CH2:28][CH2:29][CH2:30]1>>[CH3:1][C:2]1([CH3:12])[NH:3][C:4](=[O:11])[c:5]2[cH:6][c:7]([NH2:14])[cH:8][cH:9][c:10]21

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 1380612-Cyanobenzoic acidHCID 105111753,3-dimethyl-2,3-dihydro-1H-isoindol-1-oneHCID 178418348HCID 178418348, compound

Product 1

HCID 592762466-Amino-2,3-dihydro-3,3-dimethyl-1H-isoindol-1-one

Sources & evidence

ORD record
ord-804388ade6d34e7ba1ddd5dcbebb462d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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