Toluene → 3-(3-Chloro-4-trifluoromethoxy-phenylamino)-propionic acid tert-butyl ester

HRID 175703

Reaction equation

HRID 175703 reaction equation
[Br:22][CH2:23][CH2:24][C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31].[CH3:32][c:33]1[cH:34][cH:35][cH:36][cH:37][cH:38]1.[Cl:1][c:2]1[cH:3][c:4]([NH2:13])[cH:5][cH:6][c:7]1[O:8][C:9]([F:10])([F:11])[F:12].[n:14]1[c:15]([CH3:16])[cH:17][cH:18][cH:19][c:20]1[CH3:21]>>[Cl:1][c:2]1[cH:3][c:4]([NH:13][CH2:23][CH2:24][C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[cH:5][cH:6][c:7]1[O:8][C:9]([F:10])([F:11])[F:12]

Participants

5

Reactant 4

HCID 1140TolueneHCID 79372,6-LutidineHCID 256128tert-Butyl 3-bromopropionateHCID 27738433-Chloro-4-(trifluoromethoxy)aniline

Product 1

HCID 670747983-(3-Chloro-4-trifluoromethoxy-phenylamino)-propionic acid tert-butyl ester

Sources & evidence

ORD record
ord-d6a172298f9b4203b3dca341fc725647
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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