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Ethylene Glycol → 3-Chloro-5-(2-hydroxyethoxy)pyridine

HRID 175722
Notes
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Reaction equation

HRID 175722 reaction equation
[CH3:16][S:17](=[O:18])[CH3:19].[Cl:6][c:7]1[cH:8][n:9][cH:10][c:11]([Cl:13])[cH:12]1.[Na+:15].[Na:1].[OH-:14].[OH:2][CH2:3][CH2:4][OH:5]>>[O:2]([CH2:3][CH2:4][OH:5])[c:11]1[cH:10][n:9][cH:8][c:7]([Cl:6])[cH:12]1
ParticipantsSources & evidenceReaction notes

Participants

7

Reactant 6

HCID 174Ethylene GlycolHCID 679Dimethyl SulfoxideHCID 923Sodium IonHCID 961HydroxideHCID 171533,5-DichloropyridineHCID 5360545Sodium

Product 1

HCID 115573693-Chloro-5-(2-hydroxyethoxy)pyridine

Sources & evidence

ORD record
ord-fab1ba08a7c344a6a0e6490b46c4ead2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI
10.1039/C8SC04228D

Reaction notes

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On this pageParticipantsSources & evidenceReaction notes