p-Anisoyl chloride → (2-Butyl-5-nitrobenzofuran-3-yl)(4-methoxyphenyl)methanone

HRID 1761258

Reaction equation

HRID 1761258 reaction equation
[CH2:1]([C:5]1[O:6][C:7]2[CH:13]=[CH:12][C:11]([N+:14]([O-:16])=[O:15])=[CH:10][C:8]=2[CH:9]=1)[CH2:2][CH2:3][CH3:4].[C:17](Cl)(=[O:26])[C:18]1[CH:23]=[CH:22][C:21]([O:24][CH3:25])=[CH:20][CH:19]=1.[Sn](Cl)(Cl)(Cl)Cl>>[CH2:1]([C:5]1[O:6][C:7]2[CH:13]=[CH:12][C:11]([N+:14]([O-:16])=[O:15])=[CH:10][C:8]=2[C:9]=1[C:17](=[O:26])[C:18]1[CH:23]=[CH:22][C:21]([O:24][CH3:25])=[CH:20][CH:19]=1)[CH2:2][CH2:3][CH3:4]

Participants

4

Reactant 3

HCID 7477p-Anisoyl chlorideHCID 24287Tin tetrachlorideHCID 98373582-Butyl-5-nitrobenzofuran

Product 1

HCID 22595055(2-Butyl-5-nitrobenzofuran-3-yl)(4-methoxyphenyl)methanone

Procedure

reaction of 2-butyl-5-nitrobenzofuran with anisoyl chloride in the presence of tin tetrachloride according to the conditions of the Friedel-Crafts reaction and hydrolysis to form 2-butyl-3-(4-methoxybenzoyl)-5-nitrobenzofuran,

Workup

  1. customto the conditions of the Friedel-Crafts reaction and hydrolysis

Sources & evidence

ORD record
ord-f096f9743a1e447599c0beccb176fb16
Source dataset
uspto-grants-2005_01
Patent number
US06846936B2

Linked notes

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