Sodium ion → 3-[[3,5-bis(trifluoromethyl)phenyl]methyl]-5-[2-iodo-5-(trifluoromethyl)phenyl]-4-methyl-1,3-oxazolidin-2-one

HRID 176520

Reaction equation

HRID 176520 reaction equation
[Br:21][CH2:22][c:23]1[cH:24][c:25]([C:33]([F:34])([F:35])[F:36])[cH:26][c:27]([C:29]([F:30])([F:31])[F:32])[cH:28]1.[CH2:37]1[O:38][CH2:39][CH2:40][CH2:41]1.[H-:19].[I:1][c:2]1[c:3]([CH:12]2[CH:13]([CH3:18])[NH:14][C:15](=[O:17])[O:16]2)[cH:4][c:5]([C:8]([F:9])([F:10])[F:11])[cH:6][cH:7]1.[Na+:20]>>[I:1][c:2]1[c:3]([CH:12]2[CH:13]([CH3:18])[N:14]([CH2:22][c:23]3[cH:24][c:25]([C:33]([F:34])([F:35])[F:36])[cH:26][c:27]([C:29]([F:30])([F:31])[F:32])[cH:28]3)[C:15](=[O:17])[O:16]2)[cH:4][c:5]([C:8]([F:9])([F:10])[F:11])[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 923Sodium ionHCID 8028TetrahydrofuranHCID 1225733,5-Bis(trifluoromethyl)benzyl bromideHCID 166653HydrideHCID 591351365-[2-Iodo-5-(trifluoromethyl)phenyl]-4-methyl-1,3-oxazolidin-2-one

Product 1

HCID 1784220063-[[3,5-bis(trifluoromethyl)phenyl]methyl]-5-[2-iodo-5-(trifluoromethyl)phenyl]-4-methyl-1,3-oxazolidin-2-one

Sources & evidence

ORD record
ord-87355ea7348942a0a5fe018dc680c222
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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