Benzaldehyde → (S)-methyl 2-(benzylamino)propanoate
Reaction equation
[CH:1](=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.Cl.[NH2:10][C@H:11]([CH3:16])[C:12]([O:14][CH3:15])=[O:13]>>[CH2:1]([NH:10][C@@H:11]([CH3:16])[C:12]([O:14][CH3:15])=[O:13])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1Participants
3
Procedure
Prepared as in Example 12-1b from benzaldehyde and (R)-methyl 2-aminopropanoate hydrochloride. Yield 95%. MS 194 (MH+).
Sources & evidence
- ORD record
- ord-0a083cba39764fdeb1bcf7ac743789f2
- Source dataset
- uspto-grants-2016_02
- Patent number
- US09247759B2
Reaction notes
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