Hydrochloric Acid → ethyl (2RS,3RS)-3-(4-fluorophenyl)-3-hydroxy-2-((4-(trifluoromethyl)phenyl)methyl)propionate
Reaction equation
[BH4-:27].[CH3:30][OH:31].[ClH:29].[F:1][c:2]1[cH:3][cH:4][c:5]([C:8]([CH:9]([C:10](=[O:11])[O:12][CH2:13][CH3:14])[CH2:15][c:16]2[cH:17][cH:18][c:19]([C:22]([F:23])([F:24])[F:25])[cH:20][cH:21]2)=[O:26])[cH:6][cH:7]1.[Na+:28]>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([CH:9]([C:10](=[O:11])[O:12][CH2:13][CH3:14])[CH2:15][c:16]2[cH:17][cH:18][c:19]([C:22]([F:23])([F:24])[F:25])[cH:20][cH:21]2)[OH:26])[cH:6][cH:7]1Participants
6
Sources & evidence
- ORD record
- ord-c89103794fdb451295c8c375ca39a4d6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
Loading…