Formic Acid → Ethyl 3-methoxy-4-((1-methylpiperidin-4-yl)methoxy)benzoate

Reaction equation

[CH2:1]=[O:2].[CH3:32][CH2:33][O:34][CH2:35][CH3:36].[CH3:3][O:4][c:5]1[cH:6][c:7]([C:8](=[O:9])[O:10][CH2:11][CH3:12])[cH:13][cH:14][c:15]1[O:16][CH2:17][CH:18]1[CH2:19][CH2:20][N:21]([C:24]([O:25][C:26]([CH3:27])([CH3:28])[CH3:29])=[O:30])[CH2:22][CH2:23]1.[CH:38]([OH:39])=[O:40].[ClH:31].[OH2:37]>>[CH3:3][O:4][c:5]1[cH:6][c:7]([C:8](=[O:9])[O:10][CH2:11][CH3:12])[cH:13][cH:14][c:15]1[O:16][CH2:17][CH:18]1[CH2:19][CH2:20][N:21]([CH3:24])[CH2:22][CH2:23]1

Participants

Reactant 6

HCID 284Formic Acid

HCID 313Hydrochloric Acid

HCID 712Formaldehyde

HCID 962Water

HCID 3283Diethyl Ether

HCID 21874806tert-Butyl 4-((4-(ethoxycarbonyl)-2-methoxyphenoxy)methyl)piperidine-1-carboxylate

Product 1

Sources & evidence

ORD record: ord-3b8be1f6f9ce4207824ee379eddceae1
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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