Bromide ion → Ethyl 3-(2-(((2-(5,5-dimethyl-1-cyclopenten-1-yl)-2'-fluoro-5'-(methyloxy)-1,1'-biphenyl-4-yl)methyl)oxy)-4-pyridinyl)propanoate

HRID 178123

Reaction equation

HRID 178123 reaction equation
[Br-:32].[Br:1][c:2]1[cH:3][c:4]([O:8][CH2:9][c:10]2[cH:11][c:12]([C:25]3=[CH:26][CH2:27][CH2:28][C:29]3([CH3:30])[CH3:31])[c:13](-[c:16]3[c:17]([F:24])[cH:18][cH:19][c:20]([O:22][CH3:23])[cH:21]3)[cH:14][cH:15]2)[n:5][cH:6][cH:7]1.[CH2:33]([CH3:34])[O:35][C:36]([CH2:37][CH2:38][Zn+:39])=[O:40].[CH2:41]1[O:42][CH2:43][CH2:44][CH2:45]1>>[c:2]1([CH2:38][CH2:37][C:36]([O:35][CH2:33][CH3:34])=[O:40])[cH:3][c:4]([O:8][CH2:9][c:10]2[cH:11][c:12]([C:25]3=[CH:26][CH2:27][CH2:28][C:29]3([CH3:30])[CH3:31])[c:13](-[c:16]3[c:17]([F:24])[cH:18][cH:19][c:20]([O:22][CH3:23])[cH:21]3)[cH:14][cH:15]2)[n:5][cH:6][cH:7]1

Participants

5

Reactant 4

HCID 259Bromide ionHCID 8028TetrahydrofuranHCID 577058284-Bromo-2-(((2-(5,5-dimethyl-1-cyclopenten-1-yl)-2'-fluoro-5'-(methyloxy)-1,1'-biphenyl-4-yl)methyl)oxy)pyridineHCID 178471815HCID 178471815, compound

Product 1

HCID 57706923Ethyl 3-(2-(((2-(5,5-dimethyl-1-cyclopenten-1-yl)-2'-fluoro-5'-(methyloxy)-1,1'-biphenyl-4-yl)methyl)oxy)-4-pyridinyl)propanoate

Sources & evidence

ORD record
ord-f6c37f4d44254616848f9522d0d1b028
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

Loading…