3-Methyl-4-((6-methylpyridin-3-yl)oxy)aniline → HCID 57597247, compound
Reaction equation
Cl[C:2]1[C:3]2[N:10]([CH2:11][CH3:12])[CH:9]=[CH:8][C:4]=2[N:5]=[CH:6][N:7]=1.[CH3:13][C:14]1[CH:15]=[C:16]([CH:18]=[CH:19][C:20]=1[O:21][C:22]1[CH:23]=[N:24][C:25]([CH3:28])=[CH:26][CH:27]=1)[NH2:17]>CN1CCCC1=O>[CH2:11]([N:10]1[C:3]2[C:2]([NH:17][C:16]3[CH:18]=[CH:19][C:20]([O:21][C:22]4[CH:23]=[N:24][C:25]([CH3:28])=[CH:26][CH:27]=4)=[C:14]([CH3:13])[CH:15]=3)=[N:7][CH:6]=[N:5][C:4]=2[CH:8]=[CH:9]1)[CH3:12]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
To a solution of 4-chloro-5-ethyl-5H-pyrrolo[3,2-d]pyrimidine (85 mg) in 1-methyl-2-pyrrolidone (0.94 mL) was added 3-methyl-4-[(6-methylpyridin-3-yl)oxy]aniline (150 mg). The title compound (67 mg) was obtained as white powder crystals by the reaction in the same manner as in Example 29.