Hydrochloric Acid → 2-((5-Bromo-3-pyridinyl)methylene)-1-azabicyclo[2.2.2]octan-3-ol

HRID 179075

Reaction equation

HRID 179075 reaction equation
[BH4-:37].[Br:1][c:2]1[cH:3][c:4]([CH:5]=[O:6])[cH:7][n:8][cH:9]1.[Br:20][c:21]1[cH:22][c:23]([CH:27]=[C:28]2[N:29]3[CH2:30][CH2:31][CH:32]([C:33]2=[O:34])[CH2:35][CH2:36]3)[cH:24][n:25][cH:26]1.[ClH:10].[N:11]12[CH2:12][CH2:13][CH:14]([CH2:15][CH2:16]1)[C:17](=[O:18])[CH2:19]2.[Na+:38]>>[Br:20][c:21]1[cH:22][c:23]([CH:27]=[C:28]2[N:29]3[CH2:30][CH2:31][CH:32]([CH:33]2[OH:34])[CH2:35][CH2:36]3)[cH:24][n:25][cH:26]1

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 923Sodium ionHCID 195073-QuinuclidinoneHCID 28123BorohydrideHCID 27847345-Bromo-3-pyridinecarboxaldehydeHCID 545251862-((5-Bromo-3-pyridinyl)methylene)-1-azabicyclo[2.2.2]octan-3-one

Product 1

HCID 667731012-((5-Bromo-3-pyridinyl)methylene)-1-azabicyclo[2.2.2]octan-3-ol

Sources & evidence

ORD record
ord-f5b81153863543a9a14849bd46aaf48d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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