N,N-Dimethylaniline → 4-Chloro-6-(pyridin-4-yl)pyrimidin-2-amine

HRID 179648

Reaction equation

HRID 179648 reaction equation
[CH3:20][N:21]([c:22]1[cH:23][cH:24][cH:25][cH:26][cH:27]1)[CH3:28].[NH2:1][c:2]1[n:3][c:4](-[c:9]2[cH:10][cH:11][n:12][cH:13][cH:14]2)[cH:5][c:6]([OH:8])[n:7]1.[P:15]([Cl:16])([Cl:17])([Cl:18])=[O:19]>>[NH2:1][c:2]1[n:3][c:4](-[c:9]2[cH:10][cH:11][n:12][cH:13][cH:14]2)[cH:5][c:6]([Cl:17])[n:7]1

Participants

4

Reactant 3

HCID 949N,N-DimethylanilineHCID 24813Phosphorus oxychlorideHCID 178508969HCID 178508969, compound

Product 1

HCID 223242864-Chloro-6-(pyridin-4-yl)pyrimidin-2-amine

Sources & evidence

ORD record
ord-f9496b8cb3f54d18924728734accdadb
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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