Dimethylformamide → 1-(Bicyclo[2.2.1]hept-2-ylacetyl)-4-[3-(trifluoromethyl)pyridin-2-yl]piperazine

HRID 179829

Reaction equation

HRID 179829 reaction equation
[CH3:55][N:56]([CH3:57])[CH:58]=[O:59].[CH:17]12[CH:18]([CH2:24][C:25](=[O:26])[OH:27])[CH2:19][CH:20]([CH2:21][CH2:22]1)[CH2:23]2.[F:1][C:2]([c:3]1[c:4]([N:9]2[CH2:10][CH2:11][NH:12][CH2:13][CH2:14]2)[n:5][cH:6][cH:7][cH:8]1)([F:15])[F:16].[P-:28]([F:29])([F:30])([F:31])([F:32])([F:33])[F:34].[n:35]1([O:36][P+:37]([N:38]([CH3:39])[CH3:40])([N:41]([CH3:42])[CH3:43])[N:44]([CH3:45])[CH3:46])[c:47]2[cH:48][cH:49][cH:50][cH:51][c:52]2[n:53][n:54]1>>[F:1][C:2]([c:3]1[c:4]([N:9]2[CH2:10][CH2:11][N:12]([C:25]([CH2:24][CH:18]3[CH:17]4[CH2:22][CH2:21][CH:20]([CH2:19]3)[CH2:23]4)=[O:26])[CH2:13][CH2:14]2)[n:5][cH:6][cH:7][cH:8]1)([F:15])[F:16]

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 9886HexafluorophosphateHCID 79139Norborn-2-ylacetic acidHCID 124335Benzotriazol-1-yloxy-tris(dimethylamino)phosphoniumHCID 27777861-[3-(Trifluoromethyl)pyridin-2-yl]piperazine

Product 1

HCID 685521491-(Bicyclo[2.2.1]hept-2-ylacetyl)-4-[3-(trifluoromethyl)pyridin-2-yl]piperazine

Sources & evidence

ORD record
ord-cd93e17bebc74231bfa6404e85f72eb8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

Loading…