Hydrochloric Acid → 5-Morpholinopyridin-2-amine

HRID 180868

Reaction equation

HRID 180868 reaction equation
[CH3:57][OH:58].[ClH:59].[N+:37]([O-:38])(=[O:39])[c:40]1[cH:41][cH:42][c:43]([N:46]2[CH2:47][CH2:48][O:49][CH2:50][CH2:51]2)[cH:44][n:45]1.[OH2:52].[OH2:53].[Sn:54]([Cl:55])[Cl:56].[n:1]1[cH:2][cH:3][cH:4][cH:5][c:6]1-[c:7]1[n:8][n:9][n:10](-[c:11]2[cH:12][cH:13][c:14]([NH:15][c:16]3[c:17]4[n:18]([cH:19][cH:20][n:21]4)[c:22](-[c:23]4[cH:24][cH:25][c:26]([C:27]([NH2:28])=[O:29])[cH:30][cH:31]4)[cH:32][n:33]3)[cH:34][cH:35]2)[cH:36]1>>[NH2:37][c:40]1[cH:41][cH:42][c:43]([N:46]2[CH2:47][CH2:48][O:49][CH2:50][CH2:51]2)[cH:44][n:45]1

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 887MethanolHCID 962Water2×HCID 24479Stannous ChlorideHCID 29279734-(6-Nitropyridin-3-yl)morpholineHCID 177573324-{8-[4-(4-Pyridin-2-yl-[1,2,3]triazol-1-yl)-phenylamino]-imidazo[1,2-a]pyrazin-5-yl}-benzamide

Product 1

HCID 113673465-Morpholinopyridin-2-amine

Sources & evidence

ORD record
ord-3ff88ee0e0d141e5926d30449400cefc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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