Methanol → 6-chloro-2-{[2-(3-fluorophenyl)-1H-imidazol-1-yl]methyl}-3-propylimidazo[1,2-a]pyridine

HRID 181009

Reaction equation

HRID 181009 reaction equation
[CH3:28][OH:29].[CH3:33][CH2:34][O:35][C:36]([CH3:37])=[O:38].[Cl:13][CH2:14][c:15]1[n:16][c:17]2[n:18]([cH:19][c:20]([Cl:23])[cH:21][cH:22]2)[c:24]1[CH2:25][CH2:26][CH3:27].[Cl:30][CH2:31][Cl:32].[F:1][c:2]1[cH:3][c:4](-[c:8]2[nH:9][cH:10][cH:11][n:12]2)[cH:5][cH:6][cH:7]1>>[F:1][c:2]1[cH:3][c:4](-[c:8]2[n:9][cH:10][cH:11][n:12]2[CH2:14][c:15]2[n:16][c:17]3[n:18]([cH:19][c:20]([Cl:23])[cH:21][cH:22]3)[c:24]2[CH2:25][CH2:26][CH3:27])[cH:5][cH:6][cH:7]1

Participants

6

Reactant 5

HCID 887MethanolHCID 6344DichloromethaneHCID 8857Ethyl AcetateHCID 3168162-(3-fluorophenyl)-1H-imidazoleHCID 223351072-Chloromethyl-6-chloro-3-(1-propyl)-imidazolo[1,2-a]pyridine

Product 1

HCID 223350846-chloro-2-{[2-(3-fluorophenyl)-1H-imidazol-1-yl]methyl}-3-propylimidazo[1,2-a]pyridine

Sources & evidence

ORD record
ord-366c000bfd744145b7bdc9a12f3187a9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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