4-Phenoxybenzoic acid → HCID 22494095, compound
Reaction equation
O([C:8]1[CH:16]=[CH:15][C:11]([C:12]([OH:14])=O)=[CH:10][CH:9]=1)C1C=CC=CC=1.[NH2:17][CH2:18][C:19]1[CH:20]=[C:21]([CH2:27][CH:28]([O:34][CH:35]([CH3:37])[CH3:36])[C:29]([O:31]CC)=[O:30])[CH:22]=[CH:23][C:24]=1[O:25][CH3:26]>>[CH:35]([O:34][CH:28]([CH2:27][C:21]1[CH:22]=[CH:23][C:24]([O:25][CH3:26])=[C:19]([CH2:18][NH:17][C:12](=[O:14])[C:11]2[CH:10]=[CH:9][C:8]([C:8]3[CH:16]=[CH:15][CH:11]=[CH:10][CH:9]=3)=[CH:16][CH:15]=2)[CH:20]=1)[C:29]([OH:31])=[O:30])([CH3:36])[CH3:37]Participants
3
Procedure
Using 4-phenoxybenzoic acid and ethyl 3-[3-(aminomethyl)-4-methoxyphenyl]-2-isopropoxypropanoate, 2-isopropoxy-3-(4-methoxy-3-[(4-phenylbenzoyl)amino]methylphenyl)propanoic acid was obtained in the same method as in Example 19d) and then in Example 19e)
Sources & evidence
- ORD record
- ord-cb5f074b72084d06a382f1412998fde9
- Source dataset
- uspto-grants-2005_04