Sodium Ion → N-[3-bromo-5-methyl-pyridin-2-yl]-4,6-dimethyl-2-pyrimidinamine

Reaction equation

[Cl:10][c:11]1[n:12][c:13]([CH3:18])[cH:14][c:15]([CH3:17])[n:16]1.[H-:20].[NH2:1][c:2]1[n:3][cH:4][c:5]([CH3:9])[cH:6][c:7]1[Br:8].[Na+:19].[O:21]=[CH:22][N:23]([CH3:24])[CH3:25]>>[NH:1]([c:2]1[n:3][cH:4][c:5]([CH3:9])[cH:6][c:7]1[Br:8])[c:11]1[n:12][c:13]([CH3:18])[cH:14][c:15]([CH3:17])[n:16]1

Participants

Reactant 5

HCID 923Sodium Ion

HCID 6228Dimethylformamide

HCID 205502-Chloro-4,6-dimethylpyrimidine

HCID 166653Hydride

HCID 5193802-Amino-3-bromo-5-methylpyridine

Product 1

HCID 18323693N-[3-bromo-5-methyl-pyridin-2-yl]-4,6-dimethyl-2-pyrimidinamine

Sources & evidence

ORD record: ord-085e851acdfc48da9dc098ea31adbbfd
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

Reaction notes

Loading…