Hydrochloric Acid → 2-Bromo-1-(4-ethylphenyl)ethan-1-one

HRID 1825458

Reaction equation

HRID 1825458 reaction equation
[CH2:1]([C:3]1[CH:8]=[CH:7][C:6]([C:9](=[O:11])[CH3:10])=[CH:5][CH:4]=1)[CH3:2].Cl.[Br:13]Br>C(OCC)C.C(Cl)(Cl)Cl>[Br:13][CH2:10][C:9]([C:6]1[CH:7]=[CH:8][C:3]([CH2:1][CH3:2])=[CH:4][CH:5]=1)=[O:11]

Participants

6

Reactant 3

HCID 313Hydrochloric AcidHCID 136424'-EthylacetophenoneHCID 24408Bromine

Product 1

HCID 124019512-Bromo-1-(4-ethylphenyl)ethan-1-one

Reagents, catalysts & solvents 2

HCID 3283Diethyl EtherSolventHCID 6212ChloroformSolvent

Procedure

20 mmol of 1-(4-ethylphenyl)ethan-1-one, 1 ml conc. HCl were mixed in 20 ml diethyl ether at 0° C. under nitrogen. To this solution a solution of 20 mmol Br2 in 20 ml chloroform was added drop wise and left for four hours and then concentrated in vacuo to obtain 2-bromo-1-(4-ethylphenyl)ethan-1-one.

Workup

  1. concentrationconcentrated in vacuo

Sources & evidence

ORD record
ord-d84570eeeb684c5bb40cacc334df1433
Source dataset
uspto-grants-2006_05
Patent number
US07045519B2

Linked notes

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