Tegafur → 5-Fluoro-1-(oxolan-2-yl)pyrimidine-2,4-dione;palladium

HRID 1828323

Reaction equation

HRID 1828323 reaction equation
[CH2:1]1[CH2:5][O:4][CH:3]([N:6]2[C:12](=[O:13])[NH:11][C:9](=[O:10])[C:8]([F:14])=[CH:7]2)[CH2:2]1.[Pd:15]>>[Pd:15].[CH2:1]1[CH2:5][O:4][CH:3]([N:6]2[C:12](=[O:13])[NH:11][C:9](=[O:10])[C:8]([F:14])=[CH:7]2)[CH2:2]1

Participants

3

Reactant 2

HCID 5386TegafurHCID 23938Palladium

Product 1

HCID 1317224045-Fluoro-1-(oxolan-2-yl)pyrimidine-2,4-dione;palladium

Procedure

Catalyst 3C is made according to the procedure of Comparative Catalyst 3A, except that Catalyst 1B (16 g) is used in place of the spray dried TS-1. The dried solid contains 0.1 wt. % Pd and 1.8 wt. % Ti.

Sources & evidence

ORD record
ord-2e0aa8c8ddab4ef480e7a6978c32017a
Source dataset
uspto-grants-2006_06
Patent number
US07057056B1

Linked notes

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