2,4-Dichlorobenzoyl chloride → HCID 178491588, compound

Reaction equation

ClC1C=C(Cl)C=CC=1[C:4](Cl)=[O:5].Cl[C:13]1[CH:28]=[CH:27][C:16]([C:17]([NH:19][C:20]2[CH:21]=[N:22][C:23]([OH:26])=[CH:24][CH:25]=2)=[O:18])=[CH:15][CH:14]=1>>[OH:26][C:23]1[N:22]=[CH:21][C:20]([NH:19][C:17](=[O:18])[C:16]2[CH:27]=[CH:28][C:13]([O:5][CH3:4])=[CH:14][CH:15]=2)=[CH:25][CH:24]=1

Participants

Reactant 2

HCID 666452,4-Dichlorobenzoyl chloride

HCID 178522254HCID 178522254, compound

Product 1

HCID 178491588HCID 178491588, compound

Procedure

Starting from 2,4-dichlorobenzoyl chloride (2.10 g, 10.0 mmol) and using the procedure as described for the preparation of 4-Chloro-N-(6-hydroxy-pyridin-3-yl)-benzamide yielded the title compound, which was used without further purification.

Sources & evidence

ORD record: ord-830003a4046240df9a32526f044fa683
Source dataset: uspto-grants-2006_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07067517B2

Reaction notes

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