4-Bromophenol → 4-bromophenyl(2R)-3-chloro-2-methylpropyl ether
Reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([OH:8])=[CH:4][CH:3]=1.Br[CH2:10][C@@H:11]([CH3:14])[CH2:12][Cl:13]>>[Cl:13][CH2:12][C@H:11]([CH3:14])[CH2:10][O:8][C:5]1[CH:6]=[CH:7][C:2]([Br:1])=[CH:3][CH:4]=1Participants
3
Procedure
Prepared by Procedure U and Scheme AK using 4-bromophenol and (2S)-1-bromo-3-chloro-2-methylpropane.
Workup
- customPrepared by Procedure U and Scheme AK
Sources & evidence
- ORD record
- ord-7951f95aae1f42ddb032ab434326627d
- Source dataset
- uspto-grants-2006_06
- Patent number
- US07067534B1
Reaction notes
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