3-Chlorophenol → 1-Chloro-3-{[(2R)-3-chloro-2-methylpropyl]oxy}benzene
Reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([OH:8])[CH:5]=[CH:6][CH:7]=1.Br[CH2:10][C@@H:11]([CH3:14])[CH2:12][Cl:13]>>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([O:8][CH2:10][C@@H:11]([CH3:14])[CH2:12][Cl:13])[CH:3]=1Participants
3
Procedure
Prepared by Procedure U and Scheme AK using 3-chlorophenol and (2S)-1-bromo-3-chloro-2-methylpropane.
Workup
- customPrepared by Procedure U and Scheme AK
Sources & evidence
- ORD record
- ord-66bb7c04622a403a865768273678f8ed
- Source dataset
- uspto-grants-2006_06
- Patent number
- US07067534B1
Reaction notes
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