Bromide ion → Tert-butyl 3-[tert-butyl(dimethyl)silyl]oxy-2-(1-hydroxyethyl)pyrrolidine-1-carboxylate

HRID 183285

Reaction equation

HRID 183285 reaction equation
[Br-:23].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH:21]=[O:22])[CH:10]([O:13][Si:14]([CH3:15])([CH3:16])[C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:11][CH2:12]1.[CH2:26]1[O:27][CH2:28][CH2:29][CH2:30]1.[CH3:24][Mg+:25]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH:21]([OH:22])[CH3:24])[CH:10]([O:13][Si:14]([CH3:15])([CH3:16])[C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:11][CH2:12]1

Participants

5

Reactant 4

HCID 259Bromide ionHCID 8028TetrahydrofuranHCID 147351353-(tert-Butyldimethylsilanyloxy)-2-formylpyrrolidine-1-carboxylic acid tert-butyl esterHCID 178477777HCID 178477777, compound

Product 1

HCID 66878334Tert-butyl 3-[tert-butyl(dimethyl)silyl]oxy-2-(1-hydroxyethyl)pyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-98091c3a083b46d5a8ba6f27dc220ede
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

Loading…