HCID 12736922, compound → HCID 12736925, compound
Reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[O:14][C:13]3[C:12](=[O:15])[C:11]([C:16]([O:18]CC)=[O:17])=[CH:10][NH:9][C:8]=3[C:7](=[O:21])[C:6]=2[CH:22]=1>Cl>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[O:14][C:13]3[C:12](=[O:15])[C:11]([C:16]([OH:18])=[O:17])=[CH:10][NH:9][C:8]=3[C:7](=[O:21])[C:6]=2[CH:22]=1Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
A suspension of ethyl 8-chloro-4,10-dihydro-4,10-dioxo-1H-1-benzopyrano[3,2-b]pyridine-3-carboxylate (3.0 g, 0.0094 mole) in 6N hydrochloric acid (100 ml ) was refluxed under nitrogen for 15 hrs., cooled and filtered. The residue was washed with water and with acetone. Recrystallization from DMF gave white crystals (2.4 g, 87%), m.p. 325°-327°.
Workup
- temperaturewas refluxed under nitrogen for 15 hrs
- temperature, cooled
- filtrationfiltered